What gave ancient Egyptian royalty heart disease? Did inflammation from parasites cause calcification of the arteries around the heart?
Most people went barefoot or wore sandals that allowed their feet to touch the ground in places where the ground was used as an open toilet. If you go back to very early Neolithic times in Austria and Northern Italy, the Ice man mummy found had hardening of the arteries on whatever diet he ate. And what was found on him were blueberries. Which was worse, eating more butter, meat, and cheese, or eating more grains, fruits and vegetables? That depends upon how your body responds to either of these foods in excess.
See All Voices for an interesting read.